p53 Protein, Clone DO-7, FLEX RTU, Antibody Solution: Dako Omnis, 12 ml

p53 Protein, Clone DO-7, FLEX RTU. Specifications:- Antibody Solution: Dako Omnis. Clone: DO-7. Code No: GA616. EAN/UPC Code: 05700572033189. Form/Configuration: Ready-to-Use, FLEX. Full Product Name: FLEX Monoclonal Mouse Anti-Human p53 Protein, Clone DO-7, Ready-to-Use (Dako Omnis). Immunogen: Recombinant human wild-type p53 protein (1). See package insert for reference(s). Isotype: IgG2b, kappa. JAN Code: 4987582501544. Number of Tests: 60. Pathology Application: Formalin;HIER. Reagent Provided: Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide. Species: Mouse Anti-Human. Specificity (Detailed): In Western blotting of lysate of the A431 human vulval carcinoma cell line, the antibody labels a 53 kDa band, corresponding to the mutant type p53, which is expressed by A431. The epitope recognized by the antibody is located between the N-terminal amino acids 1 and 45 and possibly between amino acids 37 and 45 of the human p53 protein (1). SDS-PAGE analysis of immunoprecipitates formed between lysate of the BT474 breast cancer cell line and the antibody shows reaction with a 53 kDa protein corresponding to p53 (1). In IHC, the antibody labels mutant-type p53 in the A431 cell line and wild-type p53 in the SVK14 cell line (SV40-transformed keratinocyte line) (1). See package insert for reference(s). Volume: 12 mL.