Ki-67 Antigen, Clone MIB-1, Concentrate, 1 ml

Ki-67 Antigen, Clone MIB-1, Concentrate. Specifications:- Antibody Solution: Concentrate. Clone: MIB-1. Code No: M7240. EAN/UPC Code: 05700572006992. Form/Configuration: Culture supernatant. Full Product Name: Monoclonal Mouse Anti-Human Ki-67 Antigen, Clone MIB-1. Immunogen: Human recombinant peptide corresponding to a 1002 bp Ki-67 cDNA fragment (6). See package insert for reference(s). Isotype: IgG1, kappa. JAN Code: 4987582009194. Pathology Application: Formalin;HIER. Reagent Provided: Monoclonal mouse antibody provided in liquid form as cell culture supernatant dialysed against 0.05 mol/L Tris-HCl, 1% bovine serum albumin, pH 7.2, and containing 15 mmol/L NaN 3 . Species: Mouse Anti-Human. Specificity (Detailed): In Western blotting of lysates of the multiple myeloma cell line, IM-9, the MIB-1 antibody labels bands of 345 and 395 kDa, identical to the bands labeled by the original Ki-67 antibody. Furthermore, Western blotting and competitive binding experiments clearly demonstrate that MIB-1, like the original Ki-67 antibody, reacts with an epitope encoded by a 66 bp repetitive element in the Ki-67 gene. In IHC the MIB-1 and the Ki-67 antibodies provide identical staining patterns on serial tonsillar frozen sections (6). The MIB-1 antibody recognizes native Ki-67 antigen and recombinant fragments of the Ki-67 molecule (6). Volume: 1 mL.