Beschreibung :
Cytomegalovirus, Clone CCH2 + DDG9, FLEX RTU. Specifications:- Antibody Solution: Autostainer Link 48. Clone: CCH2 + DDG9. Code No: IR752. EAN/UPC Code: 05700572030270. Form/Configuration: Ready-to-Use, FLEX. Full Product Name: FLEX Monoclonal Mouse Anti-Cytomegalovirus, Clones CCH2 + DDG9, Ready-to-Use (Link). Immunogen: Crude cell lysates from cytomegalovirus strain Ad169-infected human embryonic fibroblasts (3). See package insert for reference(s). Isotype: IgG2a, kappa and IgG1, kappa. JAN Code: 4987582030747. Number of Tests: 60. Pathology Application: Formalin;HIER. Reagent Provided: Ready-to-use mixture of two monoclonal mouse antibodies provided in liquid form as cell culture supernatant dialysed against 0.05 mol/L Tris-HCl, 0.015 mol/L NaN 3 , pH 7.2. Species: Mouse Anti-. Specificity (Detailed): Antibody CCH2 reacts with an early nuclear protein identical with the non-structural DNA-binding protein p52 (7). More than 200 human CMV isolates have been successfully typed by this antibody which, therefore, seems to recognize an epitope which is highly conserved among HCMV strains (3, 4). Antibody DDG9 reacts with an immediate early nuclear protein of about 76 kDa (3). For both antibodies, the reactivity persists also at later stages during HCMV infection where localization is less distinctly nuclear and appears to be in the cytoplasm. Laser confocal microscopy, however, shows that the reaction is limited to the nuclear membrane (3). The antibodies do not cross-react with adenovirus, herpes simplex virus, and varicella zoster virus (3). See package insert for reference(s). Volume: 12 mL.