CD30, Clone Ber-H2, Concentrate

CD30, Clone Ber-H2, Concentrate. Specifications:- Antibody Solution: Concentrate. Clone: Ber-H2. Code No: M0751. EAN/UPC Code: 05700572005209. Form/Configuration: Culture supernatant. Full Product Name: onoclonal Mouse Anti-Human CD30, Clone Ber-H2. Immunogen: Co cell line established from a patient with Hodgkin's disease of T-cell lineage (1, 6). See package insert for reference(s). Isotype: IgG1, kappa. JAN Code: 4987582007206. Pathology Application: Frozen;Formalin;HIER. Reagent Provided: Monoclonal mouse antibody provided in liquid form as cell culture supernatant dialysed against 0.05 mol/L Tris-HCl, pH 7.2, and containing 15 mmol/L NaN 3 . Species: Mouse Anti-Human. Specificity (Detailed): The antibody was clustered as anti-CD30 at the Fourth International Workshop and Conference on Human Leucocyte Differentiation Antigens held in Vienna in 1989 (7). SDS-PAGE analysis of immunoprecipitates formed between lysate of 125 I-labeled COS cells transfected with cDNA encoding CD30 and the antibody shows reaction with a 120 kDa protein corresponding to CD30. Mock-transfected COS cells were negative. The epitope recognized by the antibody is located between amino acid residues 112 and 412 (8). The antibody labels: Cell lines derived from Hodgkin's disease, L428, L540, L591, Co, Ho and KM-H2; HTLV-1 transfected T-cell lines, Hut-102 and MT-2; EBV-transformed B-cell lines (non-Burkitt), B95-8 (monkey), BJA-B and Cess; and the myeloid cell line, K 562 (1). See package insert for reference(s). Volume: 1 mL.