CD246, ALK Protein, Clone ALK1, FLEX RTU

CD246, ALK Protein, Clone ALK1, FLEX RTU. Specifications:- Antibody Solution: Dako Omnis. Clone: ALK1. Code No: GA641. EAN/UPC Code: 05700572033110. Form/Configuration: Ready-to-Use, FLEX. Full Product Name: FLEX Monoclonal Mouse Anti-Human CD246, ALK Protein, Clone ALK1, Ready-to-Use (Dako Omnis). Immunogen: DHFR-ALK recombinant protein comprising mouse dihydrofolate reductase (DHFR) and amino acids 1359-1460 of the full length human ALK protein, corresponding to amino acids 419-520 of the chimeric NPM-ALK protein (1). See package insert for reference(s). Isotype: IgG3, kappa. JAN Code: 4987582501858. Number of Tests: 60. Pathology Application: Formalin;HIER. Reagent Provided: Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide. Species: Mouse Anti-Human. Specificity (Detailed): Anti-Human CD246, clone ALK1, was clustered as anti-CD246 at the 7th International Workshop and Conference on Human Leucocyte Differentiation Antigens (3). In Western blotting of lysate of the t(2;5)+ SU-DHL-1 cell line, the antibody labels a band of 80 kDa corresponding to NPM-ALK protein. The antibody also recognizes a band of 200 kDa corresponding to the ALK protein in the human rhabdomyosarcoma cell line Rh30 that expresses full length ALK protein, and in the 293T cell line transfected with cDNA encoding full length ALK protein. No reactivity was observed when the 293T cell line was transfected with the vector alone (1). See package insert for reference(s). Volume: 12 mL.