CD1a, Clone 010, FLEX RTU

CD1a, Clone 010, FLEX RTU. Specifications:- Antibody Solution: Autostainer Link 48. Clone: 010. Code No: IR069. EAN/UPC Code: 05700571101216. Form/Configuration: Ready-to-Use, FLEX. Full Product Name: FLEX Monoclonal Mouse Anti-Human CD1a, Clone 010, Ready-to-Use (Link). Immunogen: Human thymus cells. Isotype: IgG1, kappa. JAN Code: 4987582030570. Number of Tests: 60. Pathology Application: Formalin;HIER. Reagent Provided: Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide. Species: Mouse Anti-Human. Specificity (Detailed): Anti-Human CD1a, clone O10, was clustered as anti-CD1a at the 4th International Workshop and Conference on Human Leucocyte Differentiation Antigens (2). Clone O10 has been shown to immunoprecipitate labeled CD1a from thymus cell lysate and from Langerhans' cell-enriched epidermal cell lysate (2). In the latter, the antibody strongly precipitated the native CD1a molecule (49 kDa molecular weight) and B 2 .-microglobulin (12 kDa molecular weight) but not the trypsin-cleaved CD1a molecule (27 kDa molecular weight) (2). In IHC, the antibody has been demonstrated to react with the CD1a cell surface glycoprotein expressed on cortical thymocytes, Langerhans' cells, and interdigitating dendritic (reticulum) cells in frozen and formalin-fixed, paraffin-embedded (FFPE) tissues (1, 2). See package insert for reference(s). Volume: 12 mL.