Carcinoembryonic Antigen, Clone II-7, FLEX RTU

Carcinoembryonic Antigen, Clone II-7, FLEX RTU. Specifications:- Antibody Solution: Dako Omnis. Clone: II-7. Code No: GA622. EAN/UPC Code: 05700572033202. Form/Configuration: Ready-to-Use, FLEX. Full Product Name: FLEX Monoclonal Mouse Anti-Human Carcinoembryonic Antigen, Clone II-7, Ready-to-Use (Dako Omnis). Immunogen: Purified human CEA from liver metastasis of lung adenocarcinoma (4). See package insert for reference(s). Isotype: IgG1, kappa. JAN Code: 05700572033202. Number of Tests: 60. Pathology Application: Formalin;HIER. Reagent Provided: Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide. Species: Mouse Anti-Human. Specificity (Detailed): In ELISA, the antibody reacts with CEA preparations from both colo-rectal carcinomas, lung andenocarcinomas and the colon carcinoma cell line LS 174T, whereas the antibody does not cross-react with isolated CEA-related antigens, e.g. NCA-55, NCA-95, NCA-160 and BGP I (4). Based on ELISA, using reduced, carboxymethylated and Smith degraded CEA, the antibody is predicted to react with a conformation dependent epitope, in which the carbohydrate structures of the CEA glycoprotein are involved (4).Using solid-phase competitive immunoassays, monoclonal antibodies to CEA have been classified into five essentially non-interacting epitope groups called GOLD 1-5. Monoclonal antibodies with a high degree of CEA specificity generally belong to epitope groups GOLD 1 or 3. Monoclonal Mouse Anti-Human Carcinoembryonic Antigen (CEA), Clone II-7, belongs to epitope group GOLD 1 (8). See package insert for reference(s). Volume: 12 mL.