Amyloid A, Clone mc1, FLEX RTU

Amyloid A, Clone mc1, FLEX RTU. Specifications:- Antibody Solution: Dako Omnis. Clone: mc1. Code No: GA605. EAN/UPC Code: 05700572034179. Form/Configuration: Ready-to-Use, FLEX. Full Product Name: FLEX Monoclonal Mouse Anti-Human Amyloid A, Clone mc1, Ready-to-Use (Dako Omnis). Immunogen: An equal mixture of human amyloid A coupled to horseradish peroxidase and human amyloid A coupled to high molecular weight kininogen (5). See package insert for reference(s). Isotype: IgG2a, kappa. JAN Code: 4987582501728. Number of Tests: 60. Pathology Application: Formalin;HIER. Reagent Provided: Ready-to-use monoclonal mouse antibody provided in liquid form in a buffer containing stabilizing protein and 0.015 mol/L sodium azide. Species: Mouse Anti-Human. Specificity (Detailed): In micro-ELISA, the antibody reacts with amyloid A and the serum precursor of amyloid A indicating cross-reactivity among amyloid A protein and the serum precursor of amyloid A. In contrast, no reactivity to other non-AA amyloid fibril proteins or human serum proteins, such as albumin, transferrin, and IgG is seen (4, 5). As demonstrated by immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections, the antibody labels tissues from AA patients, but shows no reactivity with a host of unknown antigens in tissue sections of various organs (5), nor with amyloid types AK, A Lambda , and amyloid fibril proteins in familial amyloid polyneuropathy and senile cardiovascular amyloidosis, respectively. Neither are Alzheimer's amyloid plaques, amyloid in microangiopathy, lichen amyloidosis, and senile islets of Langerhans labeled by the antibody (5-7). See package insert for reference(s). Volume: 12 mL.